Stem cells: review and update

KG Sylvester, MT Longaker - Archives of surgery, 2004 - jamanetwork.com
Regenerative medicine and emerging biotechnologies stand to revolutionize the practice of
medicine. Advancements in stem cell biology, including embryonic and postnatal somatic …

Changing the paradigm of defining, detecting, and diagnosing NEC: Perspectives on Bell's stages and biomarkers for NEC

…, JR Swanson, A Maheshwari, K Sylvester - Seminars in pediatric …, 2018 - Elsevier
Better means to diagnose and define necrotizing enterocolitis are needed to guide clinical
practice and research. Adequacy of Bell's staging system for clinical practice and clarity of …

The surgical management of necrotizing enterocolitis

ZJ Kastenberg, KG Sylvester - Clinics in perinatology, 2013 - perinatology.theclinics.com
Necrotizing enterocolitis (NEC) is a common cause of neonatal gastrointestinal (GI)
morbidity and mortality. NEC is an inflammatory condition of the GI tract that occurs across a …

[HTML][HTML] Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation

RL Moss, RA Dimmitt, DC Barnhart… - … England Journal of …, 2006 - Mass Medical Soc
Background Perforated necrotizing enterocolitis is a major cause of morbidity and mortality
in premature infants, and the optimal treatment is uncertain. We designed this multicenter …

Iron-catalyzed, hydrogen-mediated reductive cyclization of 1, 6-enynes and diynes: evidence for bis (imino) pyridine ligand participation

KT Sylvester, PJ Chirik - Journal of the American Chemical …, 2009 - ACS Publications
The bis (imino) pyridine iron dinitrogen complex (iPrPDI) Fe (N2) 2 catalyzes the hydrogen-
mediated reductive cyclization of enynes and diynes with turnover frequencies comparable …

Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset

…, VD Winn, RS Gibbs, XB Ling, K Sylvester… - Science translational …, 2021 - science.org
Estimating the time of delivery is of high clinical importance because pre-and postterm
deviations are associated with complications for the mother and her offspring. However …

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway

P Viatour, U Ehmer, LA Saddic, C Dorrell… - Journal of experimental …, 2011 - rupress.org
Hepatocellular carcinoma (HCC) is the third cancer killer worldwide with> 600,000 deaths
every year. Although the major risk factors are known, therapeutic options in patients remain …

[HTML][HTML] Prediction of incident hypertension within the next year: prospective study using statewide electronic health records and machine learning

C Ye, T Fu, S Hao, Y Zhang, O Wang, B Jin… - Journal of medical …, 2018 - jmir.org
Background As a high-prevalence health condition, hypertension is clinically costly, difficult
to manage, and often leads to severe and life-threatening diseases such as cardiovascular …

Wnt/β-catenin signaling in murine hepatic transit amplifying progenitor cells

M Hu, M Kurobe, YJ Jeong, C Fuerer, S Ghole… - Gastroenterology, 2007 - Elsevier
Background & Aims: Oval cells are postnatal hepatic progenitors with high proliferative
potential and bipotent differentiation ability to become hepatocytes and cholangiocytes …

Discovery and crystallographic studies of trisubstituted piperazine derivatives as non-covalent SARS-CoV-2 main protease inhibitors with high target specificity and …

S Gao, K Sylvester, L Song, T Claff, L Jing… - Journal of Medicinal …, 2022 - ACS Publications
The continuous spread of SARS-CoV-2 calls for more direct-acting antiviral agents to
combat the highly infectious variants. The main protease (Mpro) is an promising target for …