[HTML][HTML] Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

J Lloyd-Price, C Arze, AN Ananthakrishnan… - Nature, 2019 - nature.com
Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …

Metagenomic pyrosequencing and microbial identification

JF Petrosino, S Highlander, RA Luna… - Clinical …, 2009 - academic.oup.com
Abstract Background: The Human Microbiome Project has ushered in a new era for human
metagenomics and high-throughput next-generation sequencing strategies. Content: This …

[HTML][HTML] Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders

EY Hsiao, SW McBride, S Hsien, G Sharon, ER Hyde… - Cell, 2013 - cell.com
Neurodevelopmental disorders, including autism spectrum disorder (ASD), are defined by
core behavioral impairments; however, subsets of individuals display a spectrum of …

Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons

BJ Haas, D Gevers, AM Earl, M Feldgarden… - Genome …, 2011 - genome.cshlp.org
Bacterial diversity among environmental samples is commonly assessed with PCR-
amplified 16S rRNA gene (16S) sequences. Perceived diversity, however, can be influenced …

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response

CN Spencer, JL McQuade, V Gopalakrishnan… - Science, 2021 - science.org
Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in
cancer, but the effect of diet and supplements on this interaction is not well studied. We …

[HTML][HTML] Temporal development of the gut microbiome in early childhood from the TEDDY study

CJ Stewart, NJ Ajami, JL O'Brien, DS Hutchinson… - Nature, 2018 - nature.com
The development of the microbiome from infancy to childhood is dependent on a range of
factors, with microbial–immune crosstalk during this time thought to be involved in the …

[HTML][HTML] The microbiome in precision medicine: the way forward

JF Petrosino - Genome medicine, 2018 - Springer
Editorial summary Novel associations between the human microbiome and health and
disease are routinely emerging, and important host–microbiome interactions are targets for …

[HTML][HTML] Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring

SA Buffington, GV Di Prisco, TA Auchtung, NJ Ajami… - Cell, 2016 - cell.com
Maternal obesity during pregnancy has been associated with increased risk of
neurodevelopmental disorders, including autism spectrum disorder (ASD), in offspring …

[HTML][HTML] A framework for human microbiome research

BA Methé, KE Nelson, M Pop, HH Creasy, MG Giglio… - nature, 2012 - ncbi.nlm.nih.gov
A variety of microbial communities and their genes (microbiome) exist throughout the human
body, playing fundamental roles in human health and disease. The NIH funded Human …

A catalog of reference genomes from the human microbiome

Human Microbiome Jumpstart Reference Strains … - Science, 2010 - science.org
The human microbiome refers to the community of microorganisms, including prokaryotes,
viruses, and microbial eukaryotes, that populate the human body. The National Institutes of …