Purpose Endometrial cancers have long been divided into estrogen-dependent type I and
the less common clinically aggressive estrogen-independent type II. Little is known about …

Helicobacter pylori infection is associated with a variety of clinical outcomes including
gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but …

Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility
to the disease. Known susceptibility genes account for less than 25% of the familial risk of …

Abstract Background: Human papillomavirus (HPV), the causal agent of cervical cancer,
appears to be involved in the etiology of cancer of the oral cavity and oropharynx. To …

Lung cancer is the most common cause of cancer death worldwide, with over one million
cases annually. To identify genetic factors that modify disease risk, we conducted a genome …

Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for∼ …

Background Immunohistochemical markers are often used to classify breast cancer into
subtypes that are biologically distinct and behave differently. The aim of this study was to …

Stratification of women according to their risk of breast cancer based on polygenic risk
scores (PRSs) could improve screening and prevention strategies. Our aim was to develop …

Background Previous studies have suggested that breast cancer risk factors are associated
with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors …

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …