A variety of factors have been identified that regulate angiogenesis, including the CXC
chemokine family. The CXC chemokines are a unique family of cytokines for their ability to …

CXC chemokines display pleiotropic effects in immunity, regulating angiogenesis, and
mediating organ-specific metastases of cancer. In the context of angiogenesis, CXC …

Chemokines have pleiotropic effects in regulating immunity, angiogenesis, stem cell
trafficking, and mediating organ-specific metastases of cancer. In the context of …

Previous reports have identified a circulating pool of CD45+ collagen I+ CXCR4+(CD45+
Col I+ CXCR4+) cells, termed fibrocytes, that traffic to areas of fibrosis. No studies have …

Influenza-related complications continue to be a major cause of mortality worldwide. Due to
unclear mechanisms, a substantial number of influenza-related deaths result from bacterial …

Non–small cell lung cancer is characterized by a specific metastatic pattern. The mechanism
for organ-specific metastasis is poorly understood, although evidence has suggested that …

Mortality related to adult respiratory distress syndrome (ARDS) ranges from 35% to 65%.
Lung-protective ventilator strategies can reduce mortality during ARDS. The protective …

Non-small cell lung cancer (NSCLC) expresses a particularly aggressive metastatic
phenotype, and patients with this disease have a poor prognosis. CXC chemokine receptor …

Rationale: Acute lung dysfunction of noninfectious etiology, known as idiopathic pneumonia
syndrome (IPS), is a severe complication following hematopoietic stem cell transplantation …

Abstract The Glu-Leu-Arg+(ELR+) CXC chemokines are potent promoters of angiogenesis
and have been demonstrated to induce a significant portion of nonsmall cell lung cancer …