User profiles for "author:J. Semple"

John W. Semple

Professor of Transfusion Medicine, Lund University
Verified email at med.lu.se
Cited by 13042

Platelets and the immune continuum

JW Semple, JE Italiano, J Freedman - Nature Reviews Immunology, 2011 - nature.com
Platelets are anucleate cells that are crucial mediators of haemostasis. Most immunologists
probably don't think about platelets every day, and may even consider these cells to …

Early detection and differential diagnosis of Alzheimer's disease and depression with neuropsychological tasks

R Swainson, JR Hodges, CJ Galton, J Semple… - Dementia and geriatric …, 2001 - karger.com
The development of novel treatments for Alzheimer's disease (AD), aimed at ameliorating
symptoms and modifying disease processes, increases the need for early diagnosis …

Schizophrenia and the structure of language: the linguist's view

…, L Naçi, JT McClain, BS Fjordbak, J Semple… - Schizophrenia …, 2005 - Elsevier
Patients with schizophrenia often display unusual language impairments. This is a wide
ranging critical review of the literature on language in schizophrenia since the 19th century …

[HTML][HTML] Tumor angiogenesis and metastasis—correlation in invasive breast carcinoma

N Weidner, JP Semple, WR Welch… - New England Journal …, 1991 - Mass Medical Soc
Background. Experimental evidence suggests that the growth of a tumor beyond a certain
size requires angiogenesis, which may also permit metastasis. To investigate how tumor …

[BOOK][B] Algebraic projective geometry

JG Semple, GT Kneebone - 1998 - academic.oup.com
Algebraic Projective Geometry | Oxford Academic Skip to Main Content Advertisement Oxford
Academic Search Menu Information Account Menu Information Account Navbar Search Filter …

Dynamics of gray matter loss in Alzheimer's disease

…, AL Janke, SE Rose, J Semple… - Journal of …, 2003 - Soc Neuroscience
We detected and mapped a dynamically spreading wave of gray matter loss in the brains of
patients with Alzheimer's disease (AD). The loss pattern was visualized in four dimensions …

Thrombocytopenia following pfizer and Moderna SARS‐CoV‐2 vaccination

EJ Lee, DB Cines, T Gernsheimer… - American journal of …, 2021 - Wiley Online Library
Cases of apparent secondary immune thrombocytopenia (ITP) after SARS-CoV-2
vaccination with both the Pfizer and Moderna versions have been reported and reached …

Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with colour coded MR diffusion tensor imaging

…, WE Strugnell, M Benson, J Semple… - Journal of Neurology …, 2000 - jnnp.bmj.com
A NOVEL MRI METHOD diffusion tensor imaging—was used to compare the integrity of
several white matter fibre tracts in patients with probable Alzheimer's disease. Relative to …

Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man

AM Owen, BJ Sahakian, J Semple, CE Polkey… - Neuropsychologia, 1995 - Elsevier
Three groups of neurosurgical patients with temporal lobe excisions, frontal lobe excisions
or unilateral amygdalo-hippocampectomy were assessed on a computerized battery of tasks …

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

LH Boudreau, AC Duchez, N Cloutier… - Blood, The Journal …, 2014 - ashpublications.org
Mitochondrial DNA (mtDNA) is a highly potent inflammatory trigger and is reportedly found
outside the cells in blood in various pathologies. Platelets are abundant in blood where they …