Standards of care for occupational asthma
D Fishwick, CM Barber, LM Bradshaw, J Harris-Roberts… - Thorax, 2008 - thorax.bmj.com
Occupational asthma remains a common disease in the UK with up to 3000 new cases
diagnosed each year. The Health and Safety Executive (HSE) estimates the cost to our …
diagnosed each year. The Health and Safety Executive (HSE) estimates the cost to our …
Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study
JM Corne, C Marshall, S Smith, J Schreiber… - The Lancet, 2002 - thelancet.com
Background Rhinovirus infections cause exacerbations of asthma. We postulated that
people with asthma are more susceptible to rhinovirus infection than people without the …
people with asthma are more susceptible to rhinovirus infection than people without the …
Mechanisms of virus induced exacerbations of asthma
JM Corne, ST Holgate - Thorax, 1997 - ncbi.nlm.nih.gov
Most work on the pathogenesis of asthma has loss of ciliated and non-ciliated cells from the
tracheal epithelium and the basal epithelial studied airway inflammation using allergen …
tracheal epithelium and the basal epithelial studied airway inflammation using allergen …
[HTML][HTML] Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients
RA Urbanowicz, JR Lamb, I Todd, JM Corne… - Respiratory …, 2010 - Springer
Background We have previously shown that NK (CD56+ CD3-) and NKT-like (CD56+ CD3+)
cells are reduced in both numbers and cytotoxicity in peripheral blood. The aim of the …
cells are reduced in both numbers and cytotoxicity in peripheral blood. The aim of the …
[HTML][HTML] Altered effector function of peripheral cytotoxic cells in COPD
RA Urbanowicz, JR Lamb, I Todd, JM Corne… - Respiratory …, 2009 - Springer
Background There is mounting evidence that perforin and granzymes are important
mediators in the lung destruction seen in COPD. We investigated the characteristics of the …
mediators in the lung destruction seen in COPD. We investigated the characteristics of the …
[HTML][HTML] Differential activation of killer cells in the circulation and the lung: a study of current smoking status and chronic obstructive pulmonary disease (COPD)
Background CD8+ T-lymphocytes, natural killer T-like cells (NKT-like cells, CD56+ CD3+)
and natural killer cells (NK cells, CD56+ CD3−) are the three main classes of human killer …
and natural killer cells (NK cells, CD56+ CD3−) are the three main classes of human killer …
Standards of care for occupational asthma: an update
D Fishwick, CM Barber, LM Bradshaw, JG Ayres… - Thorax, 2012 - thorax.bmj.com
Background The British Thoracic Society (BTS) Standards of Care (SoC) Committee
produced a standard of care for occupational asthma (OA) in 2008, based on a systematic …
produced a standard of care for occupational asthma (OA) in 2008, based on a systematic …
[HTML][HTML] MMP-9 protein level does not reflect overall MMP activity in the airways of patients with COPD
GE Lowrey, N Henderson, JD Blakey, JM Corne… - Respiratory …, 2008 - Elsevier
BACKGROUND: Animal and human studies have implicated an imbalance of matrix
metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in the …
metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in the …
Natural and disease-specific autoantibodies in chronic obstructive pulmonary disease
NI Daffa, PJ Tighe, JM Corne… - Clinical & …, 2015 - academic.oup.com
Autoimmunity may contribute to the pathogenesis of chronic obstructive pulmonary disease
(COPD). Studies have identified disease-specific autoantibodies (DSAAbs) in COPD …
(COPD). Studies have identified disease-specific autoantibodies (DSAAbs) in COPD …
The relationship between atopic status and IL-10 nasal lavage levels in the acute and persistent inflammatory response to upper respiratory tract infection
JM Corne, L Lau, SJ Scott, R Davies… - American journal of …, 2001 - atsjournals.org
We examined the influence of atopy on virus-induced airway inflammation by comparing the
nasal response to naturally acquired upper respiratory tract infection in atopic and nonatopic …
nasal response to naturally acquired upper respiratory tract infection in atopic and nonatopic …