Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors
H van de Waterbeemd, G Camenisch… - Journal of drug …, 1998 - Taylor & Francis
The influence of physicochemical properties, including lipophilicity, H-bonding capacity and
molecular size and shape descriptors on brain uptake has been investigated using a …
molecular size and shape descriptors on brain uptake has been investigated using a …
[HTML][HTML] Influenza forecasting in human populations: a scoping review
JP Chretien, D George, J Shaman, RA Chitale… - PloS one, 2014 - journals.plos.org
Forecasts of influenza activity in human populations could help guide key preparedness
tasks. We conducted a scoping review to characterize these methodological approaches …
tasks. We conducted a scoping review to characterize these methodological approaches …
[HTML][HTML] Beyond traditional surveillance: applying syndromic surveillance to developing settings–opportunities and challenges
L May, JP Chretien, JA Pavlin - BMC Public Health, 2009 - Springer
Background All countries need effective disease surveillance systems for early detection of
outbreaks. The revised International Health Regulations [IHR], which entered into force for …
outbreaks. The revised International Health Regulations [IHR], which entered into force for …
Online posting of unprofessional content by medical students
KC Chretien, SR Greysen, JP Chretien, T Kind - Jama, 2009 - jamanetwork.com
Context Web 2.0 applications, such as social networking sites, are creating new challenges
for medical professionalism. The scope of this problem in undergraduate medical education …
for medical professionalism. The scope of this problem in undergraduate medical education …
Prediction of a Rift Valley fever outbreak
A Anyamba, JP Chretien, J Small… - Proceedings of the …, 2009 - National Acad Sciences
El Niño/Southern Oscillation related climate anomalies were analyzed by using a
combination of satellite measurements of elevated sea-surface temperatures and …
combination of satellite measurements of elevated sea-surface temperatures and …
Epidemiology of weaning outcome according to a new definition. The WIND study
G Béduneau, T Pham, F Schortgen… - American journal of …, 2017 - atsjournals.org
Rationale: The weaning process concerns all patients receiving mechanical ventilation. A
previous classification into simple, prolonged, and difficult weaning ignored weaning failure …
previous classification into simple, prolonged, and difficult weaning ignored weaning failure …
[PDF][PDF] Drought-associated chikungunya emergence along coastal East Africa
JP Chretien, A Anyamba, SA Bedno, RF Breiman… - 2007 - academia.edu
Epidemics of chikungunya fever, an Aedes spp.-borne viral disease, affected hundreds of
thousands of people in western Indian Ocean islands and India during 2005–2006. The …
thousands of people in western Indian Ocean islands and India during 2005–2006. The …
[HTML][HTML] A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study
Introduction While prone positioning (PP) has been shown to improve patient survival in
moderate to severe acute respiratory distress syndrome (ARDS) patients, the rate of …
moderate to severe acute respiratory distress syndrome (ARDS) patients, the rate of …
Pleural effusion: laboratory tests in 300 cases.
A Hirsch, P Ruffie, M Nebut, J Bignon, J Chretien - Thorax, 1979 - thorax.bmj.com
The cause of pleural effusion was studied in 300 consecutive patients by clinical
examination and laboratory tests. The three most common causes were found to be cancer …
examination and laboratory tests. The three most common causes were found to be cancer …
[HTML][HTML] Differential susceptibility to hypertension is due to selection during the out-of-Africa expansion
JH Young, YPC Chang, JDO Kim, JP Chretien… - PLoS …, 2005 - journals.plos.org
Hypertension is a leading cause of stroke, heart disease, and kidney failure. The genetic
basis of blood pressure variation is largely unknown but is likely to involve genes that …
basis of blood pressure variation is largely unknown but is likely to involve genes that …