BACKGROUND: Patients with cystic fibrosis are known to have decreased mucociliary
clearance. It has previously been shown that inhalation of a 7.0% solution of hypertonic …

In patients with cystic fibrosis (CF), dehydration of airway secretions leads to a decrease in
mucociliary clearance (MCC). We examined the acute effect of MCC of a single …

The detailed mechanisms of oxygen-induced hypercapnia were examined in 22 patients
during an acute exacerbation of chronic obstructive pulmonary disease. Ventilation, cardiac …

The aim of this study was to examine baseline mucociliary clearance (MCC) in patients with
cystic fibrosis (n= 30; mean+/-SEM age, 23+/-1 yr; FEV1, 68+/-5% pred; range, 14 to 126%) …

Primary ciliary dyskinesia (PCD) is a genetic disease characterized by abnormal ciliary
structure and function and impaired mucociliary clearance. Because patients with PCD use …

There are no reports concerning the regulation of end-expiratory lung volume (EELV) and
flow–volume relationships during upper limb exercise in health and disease. We studied …

Study objectives Airway epithelial ion transport is an important component of the airway
defense mechanism, and new therapies that target ion transport are being developed …

This paper reports on a large retrospective analysis of mucociliary clearance (MCC) studies
in a group of 59 patients with cystic fibrosis (CF) and 17 age-matched healthy subjects. As …

Changes in end-expiratory lung volume (EELV) during exercise in normal subjects and in
patients with severe chronic obstructive lung disease have previously been examined …

Patients with cystic fibrosis (CF) often hypoventilate during sleep with marked falls in oxygen
saturation (SaO 2%). This occurs most commonly during REM sleep, when there is a …