[HTML][HTML] Human mesenchymal stem cells (MSCs) for treatment towards immune-and inflammation-mediated diseases: review of current clinical trials

LT Wang, CH Ting, ML Yen, KJ Liu, HK Sytwu… - Journal of biomedical …, 2016 - Springer
Human mesenchymal stem cells (MSCs) are multilineage somatic progenitor/stem cells that
have been shown to possess immunomodulatory properties in recent years. Initially met with …

[HTML][HTML] Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells

PM Chen, ML Yen, KJ Liu, HK Sytwu… - Journal of Biomedical …, 2011 - Springer
In recent years, a large number of studies have contributed to our understanding of the
immunomodulatory mechanisms used by multipotent mesenchymal stem cells (MSCs) …

[HTML][HTML] Role of galectins in tumors and in clinical immunotherapy

FC Chou, HY Chen, CC Kuo, HK Sytwu - International journal of …, 2018 - mdpi.com
Galectins are glycan-binding proteins that contain one or two carbohydrate domains and
mediate multiple biological functions. By analyzing clinical tumor samples, the abnormal …

[HTML][HTML] Artificial intelligence approach fighting COVID-19 with repurposing drugs

YY Ke, TT Peng, TK Yeh, WZ Huang, SE Chang… - Biomedical journal, 2020 - Elsevier
Background The ongoing COVID-19 pandemic has caused more than 193,825 deaths
during the past few months. A quick-to-be-identified cure for the disease will be a therapeutic …

SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction

SS Yang, YF Lo, CC Wu, SW Lin, CJ Yeh… - Journal of the …, 2010 - journals.lww.com
Polymorphisms in the gene encoding sterile 20/SPS1-related proline/alanine-rich kinase
(SPAK) associate with hypertension susceptibility in humans. SPAK interacts with WNK …

[PDF][PDF] The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice

HK Sytwu, RS Liblau, HO McDevitt - Immunity, 1996 - cell.com
The possible involvement of Fas/APO-1 (CD95) and TNF in antigen-specific AICD of
thymocytes and mature T cells has been investigated. Antigenic stimulation in vivo of …

[HTML][HTML] Immunologic regulation in pregnancy: from mechanism to therapeutic strategy for immunomodulation

SJ Chen, YL Liu, HK Sytwu - Journal of Immunology Research, 2012 - hindawi.com
The immunologic interaction between the fetus and the mother is a paradoxical
communication that is regulated by fetal antigen presentation and/or by recognition of and …

SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway

MT Chung, HC Lai, HK Sytwu, MD Yan, YL Shih… - Gynecologic …, 2009 - Elsevier
OBJECTIVES: Aberrant activation of the Wnt/β-catenin signaling pathway is common in
human cancers, including cervical cancer. The secreted frizzled-related proteins (SFRPs) …

Advances in mesenchymal stem cell therapy for immune and inflammatory diseases: Use of cell-free products and human pluripotent stem cell-derived mesenchymal …

LT Wang, KJ Liu, HK Sytwu, ML Yen… - Stem cells translational …, 2021 - academic.oup.com
Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to
be popular based on progressive accumulation of preclinical mechanistic evidence. This …

[PDF][PDF] Multipotent human mesenchymal stromal cells mediate expansion of myeloid-derived suppressor cells via hepatocyte growth factor/c-met and STAT3

BL Yen, ML Yen, PJ Hsu, KJ Liu, CJ Wang, CH Bai… - Stem cell reports, 2013 - cell.com
Mesenchymal stromal cells (MSCs) are multilineage progenitors with immunomodulatory
properties, including expansion of immunomodulatory leukocytes such as regulatory T …