Background Maternal smoking during pregnancy is linked to reduced birth weight but the
gestation at onset of this relationship is not certain. We present a systematic review of the …

Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome …

Folate is vital for fetal development. Periconceptional folic acid supplementation and food
fortification are recommended to prevent neural tube defects. Mechanisms whereby …

Objective Asthma is a common chronic respiratory airway disease influenced by
environmental factors and possibly their interaction with the human genome causing …

Background Children born preterm or with a small size for gestational age are at increased
risk for childhood asthma. Objective We sought to assess the hypothesis that these …

Background: Prenatal exposure to air pollution is considered to be associated with adverse
effects on child health. This may partly be mediated by mechanisms related to DNA …

Background Epigenetic mechanisms, including methylation, can contribute to childhood
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …

Background: Prenatal exposure to air pollution has been associated with childhood
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …

Allergic rhinitis is the most common clinical presentation of allergy, affecting 400 million
people worldwide, with increasing incidence in westernized countries,. To elucidate the …

Background Early-life respiratory tract infections might affect chronic obstructive respiratory
diseases, but conclusive studies from general populations are lacking. Our objective was to …