Cystic fibrosis (CF) is the most common lethal genetic disease in the Caucasian population,
and should be considered an infectious disease because of the basic pathophysiology …

The “Streptococcus milleri” group (SMG) is increasingly recognized for their role in pyogenic
infections including empyema and solid organ abscesses. However, SMG disease has …

The change in gene expression patterns in response to host environments is a prerequisite
for bacterial infection. Bacterial diseases often occur as an outcome of the complex …

Patients and Methods: Seventy-nine patients with advanced solid cancers that were
unresponsive to standard therapy were enrolled. Four PV701 intravenous dosing regimens …

Lung disease is the leading cause of morbidity and mortality in cystic fibrosis (CF) patients. A
modest number of bacterial pathogens have been correlated with pulmonary function …

Individuals with cystic fibrosis (CF) are commonly colonized with Pseudomonas aeruginosa.
The chronic infections caused by P. aeruginosa are punctuated by acute exacerbations of …

A number of human infections are characterized by the presence of more than one bacterial
species and are defined as polymicrobial diseases. Methods for the analysis of the complex …

The microbiome of the respiratory tract, including the nasopharyngeal and oropharyngeal
microbiota, is a dynamic community of microorganisms that is highly diverse. The cystic …

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lower airways
of patients with cystic fibrosis. Throughout the course of infection this organism undergoes …

A comprehensive understanding of airway infections offers the potential for improved
disease management in CF patients. Accurate quantitative microbiology will be a …