We studied the effects of acute changes in the partial pressure of arterial carbon dioxide on
diaphragmatic contractility and performance in four normal men. To study contractility we …

Background Idiopathic pulmonary fibrosis (IPF) is characterised by the aberrant epithelial to
mesenchymal transition (EMT) and myofibroblast accumulation. Sphingosine-1-phosphate …

Idiopathic pulmonary hypertension (IPAH) is a rare disease characterized by a progressive
increase in pulmonary vascular resistance leading to heart failure. MicroRNAs (miRNAs) are …

OBJECTIVE: Phrenic neuropathy after coronary artery bypass grafting has been related to
various risk factors with conflicting results. The aim of this study was to assess the incidence …

Background: Neutrophils and oxidative stress have been implicated in the pathogenesis of
COPD. Severe, early-onset COPD is characterized by a rapid decline in the lung function at …

Sildenafil improves the 6-min walking distance in patients with idiopathic pulmonary fibrosis
(IPF) and right-sided ventricular systolic dysfunction. We analysed the previously unexplored …

Idiopathic pulmonary fibrosis (IPF), a devastating progressive interstitial lung disease (ILD)
with no known cause, is the most common and deadly of the idiopathic interstitial …

Background Inhaled corticosteroid (ICS) with long-acting beta-2 agonists is a well-
documented combination therapy for chronic obstructive pulmonary disease (COPD) based …

Idiopathic Pulmonary arterial hypertension (IPAH) is characterized by the obstructive
remodelling of pulmonary arteries, and a progressive elevation in pulmonary arterial …

Cigarette smoke mediated oxidative stress and endothelial dysfunction are important
processes in the pathogenesis of several lung disorders. In this study we evaluated the …