Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study

MLN McDonald, AA Diaz, JC Ross… - Annals of the …, 2014 - atsjournals.org
Rationale: Muscle wasting in chronic obstructive pulmonary disease (COPD) is associated
with a poor prognosis and is not readily assessed by measures of body mass index (BMI) …

Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema

PJ Castaldi, J Dy, J Ross, Y Chang, GR Washko… - Thorax, 2014 - thorax.bmj.com
Background There is notable heterogeneity in the clinical presentation of patients with
COPD. To characterise this heterogeneity, we sought to identify subgroups of smokers by …

Metformin: experimental and clinical evidence for a potential role in emphysema treatment

F Polverino, TD Wu, J Rojas-Quintero… - American journal of …, 2021 - atsjournals.org
Rationale: Cigarette smoke (CS) inhalation triggers oxidative stress and inflammation,
leading to accelerated lung aging, apoptosis, and emphysema, as well as systemic …

Dexmedetomidine does not affect evoked potentials during spine surgery

I Rozet, J Metzner, M Brown, MM Treggiari… - Anesthesia & …, 2015 - journals.lww.com
BACKGROUND: The effect of dexmedetomidine on evoked potentials (EPs) has not been
elucidated. We aimed to investigate the effect of dexmedetomidine on somatosensory …

[HTML][HTML] Extensive soot compaction by cloud processing from laboratory and field observations

J Bhandari, S China, KK Chandrakar, G Kinney… - Scientific Reports, 2019 - nature.com
Soot particles form during combustion of carbonaceous materials and impact climate and air
quality. When freshly emitted, they are typically fractal-like aggregates. After atmospheric …

An atmospheric pressure chemical ionization MS/MS assay using online extraction for the analysis of 11 cannabinoids and metabolites in human plasma and urine

J Klawitter, C Sempio, S Mörlein… - Therapeutic Drug …, 2017 - journals.lww.com
Background: Although, especially in the United States, there has been a recent surge of
legalized cannabis for either recreational or medicinal purposes, surprisingly little is known …

Chest computed tomography-derived low fat-free mass index and mortality in COPD

MLN McDonald, AA Diaz, E Rutten… - European …, 2017 - Eur Respiratory Soc
Low fat-free mass index (FFMI) is an independent risk factor for mortality in chronic
obstructive pulmonary disease (COPD) not typically measured during routine care. In the …

Respiratory exacerbations are associated with muscle loss in current and former smokers

SE Mason, R Moreta-Martinez, WW Labaki, M Strand… - Thorax, 2021 - thorax.bmj.com
Objectives Muscle wasting is a recognised extra-pulmonary complication in chronic
obstructive pulmonary disease and has been associated with increased risk of death. Acute …

Automated quantitative 3D analysis of aorta size, morphology, and mural calcification distributions

S Kurugol, CE Come, AA Diaz, JC Ross… - Medical …, 2015 - Wiley Online Library
Purpose: The purpose of this work is to develop a fully automated pipeline to compute aorta
morphology and calcification measures in large cohorts of CT scans that can be used to …

Dependence of aerosol‐droplet partitioning on turbulence in a laboratory cloud

ASM Shawon, P Prabhakaran, G Kinney… - Journal of …, 2021 - Wiley Online Library
Activation is the first step in aerosol‐cloud interactions, which have been identified as one of
the principal uncertainties in Earth's climate system. Aerosol particles become cloud …