User profiles for "author:Gerard H Koppelman"
Gerard H. KoppelmanProfessor of Pediatric Pulmonology, University Medical Center Groningen Verified email at umcg.nl Cited by 32786 |
Biologic therapies for severe asthma
GG Brusselle, GH Koppelman - New England Journal of …, 2022 - Mass Medical Soc
Biologic Therapies for Severe Asthma Patients with severe asthma are at increased risk for a
decreased quality of life, fixed airway obstruction, hospitalization, and death. Biologics may …
decreased quality of life, fixed airway obstruction, hospitalization, and death. Biologics may …
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs
J Bousquet, HJ Schünemann, B Samolinski… - Journal of Allergy and …, 2012 - Elsevier
Allergic rhinitis (AR) and asthma represent global health problems for all age groups.
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact …
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact …
MACVIA‐ARIA Sentinel NetworK for allergic rhinitis (MASK‐rhinitis): the new generation guideline implementation
Several unmet needs have been identified in allergic rhinitis: identification of the time of
onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification …
onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification …
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
DF Gudbjartsson, US Bjornsdottir, E Halapi… - Nature …, 2009 - nature.com
Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of inflammatory responses and thus have important roles in the pathogenesis of …
of inflammatory responses and thus have important roles in the pathogenesis of …
[PDF][PDF] DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis
Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
A cellular census of human lungs identifies novel cell states in health and in asthma
Human lungs enable efficient gas exchange and form an interface with the environment,
which depends on mucosal immunity for protection against infectious agents. Tightly …
which depends on mucosal immunity for protection against infectious agents. Tightly …
[HTML][HTML] Patterns of growth and decline in lung function in persistent childhood asthma
Background Tracking longitudinal measurements of growth and decline in lung function in
patients with persistent childhood asthma may reveal links between asthma and subsequent …
patients with persistent childhood asthma may reveal links between asthma and subsequent …
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
JS Ried, J Li, XB Zuo, XD Zheng, XY Yin, LD Sun… - Nature …, 2015 - nature.com
Genetic association studies have identified 21 loci associated with atopic dermatitis risk
predominantly in populations of European ancestry. To identify further susceptibility loci for …
predominantly in populations of European ancestry. To identify further susceptibility loci for …
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
F Demenais, P Margaritte-Jeannin, KC Barnes… - Nature …, 2018 - nature.com
We examined common variation in asthma risk by conducting a meta-analysis of worldwide
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
MA Ferreira, JM Vonk, H Baurecht, I Marenholz… - Nature …, 2017 - nature.com
Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the
same individuals, partly because of a shared genetic origin,,. To identify shared risk variants …
same individuals, partly because of a shared genetic origin,,. To identify shared risk variants …