Using hyperpolarized 129Xe MRI to quantify regional gas transfer in idiopathic pulmonary fibrosis

JM Wang, SH Robertson, Z Wang, M He, RS Virgincar… - Thorax, 2018 - thorax.bmj.com
Background Assessing functional impairment, therapeutic response and disease
progression in patients with idiopathic pulmonary fibrosis (IPF) continues to be challenging …

Quantitative analysis of hyperpolarized 129Xe gas transfer MRI

Z Wang, SH Robertson, J Wang, M He… - Medical …, 2017 - Wiley Online Library
Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …

A protocol for quantifying cardiogenic oscillations in dynamic 129Xe gas exchange spectroscopy: The effects of idiopathic pulmonary fibrosis

EA Bier, SH Robertson, GM Schrank… - NMR in …, 2019 - Wiley Online Library
The spectral parameters of hyperpolarized 129Xe exchanging between airspaces, interstitial
barrier, and red blood cells (RBCs) are sensitive to pulmonary pathophysiology. This study …

Establishing an accurate gas phase reference frequency to quantify 129Xe chemical shifts in vivo

RS Virgincar, SH Robertson, J Nouls… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose 129Xe interacts with biological media to exhibit chemical shifts exceeding 200 ppm
that report on physiology and pathology. Extracting this functional information requires shifts …

Using hyperpolarized 129Xe imaging to quantify apical vs. basal and central vs. peripheral gas exchange impairment in idiopathic pulmonary fibrosis

JM Wang, SH Robertson, M He… - C39. IPF: MORE ON …, 2016 - atsjournals.org
RBC: Barrier were calculated to quantify regional gas exchange. For the peripheral lung,
RBC: Barrier was calculated using a mask to define 2-3 cm of the subpleural lung perimeter …

A Novel, Finite-Element Model for Spin-Exchange Optical Pumping Using an Open-Source Code

GM Schrank - arXiv preprint arXiv:1911.01574, 2019 - arxiv.org
A new model is presented for spin-exchange optical pumping using an open-source code,
ElmerFEM-CSC. The model builds on previous models by adding the effects of alkali-vapor …

[PDF][PDF] Xenon polarizer characterization and biological studies

GM Schrank - 2010 - core.ac.uk
ABSTRACT I will describe a low-pressure flow-through 129Xe polarizer and report its
performance by examining both the output 129Xe and in situ Rb polarization. The 129Xe …