[HTML][HTML] Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis

S Aguilar, CJ Scotton, K McNulty, E Nye, G Stamp… - PloS one, 2009 - journals.plos.org
Many common diseases of the gas exchange surface of the lung have no specific treatment
but cause serious morbidity and mortality. Idiopathic Pulmonary Fibrosis (IPF) is …

Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation

YP Moodley, AK Scaffidi, NL Misso… - The American journal of …, 2003 - Elsevier
Interleukin (IL)-6 and IL-11 are elevated in a variety of lung conditions and may impact on
repair mechanisms in chronic inflammatory disorders. However, the mechanisms by which …

Surveillance for the detection of early lung cancer in patients with bronchial dysplasia

PJ George, AK Banerjee, CA Read, C O'Sullivan… - Thorax, 2007 - thorax.bmj.com
Background: The natural history of bronchial preinvasive lesions and the risk of developing
lung cancer in patients with these lesions are not clear. Previous studies have treated …

[HTML][HTML] Mesenchymal stem cells as vectors for lung cancer therapy

KK Kolluri, GJ Laurent, SM Janes - Respiration, 2013 - karger.com
Despite recent advances in treatment, lung cancer accounts for one third of all cancer-
related deaths, underlining the need of development of new therapies. Mesenchymal stem …

Stem cell therapy in chronic obstructive pulmonary disease. Seeking the Prometheus effect

A Tzouvelekis, G Laurent, D Bouros - Current drug targets, 2013 - ingentaconnect.com
Chronic obstructive pulmonary disease is characterized by dramatic alterations in lung
architecture associated to an exaggerated inflammatory process, alveolar epithelial cell …

[HTML][HTML] Cancer predisposing BARD1 mutations affect exon skipping and are associated with overexpression of specific BARD1 isoforms

M Ratajska, M Matusiak, A Kuzniacka… - Oncology …, 2015 - spandidos-publications.com
BARD1 is the main binding partner of BRCA1 and is required for its stability and tumor-
suppressor functions. In breast cancer and other epithelial cell carcinomas, alternatively …

Diabetes: Present and future

I Iminger-Finger, J Kargul… - … international journal of …, 2017 - pubmed.ncbi.nlm.nih.gov
Diabetes: Present and future Diabetes: Present and future Int J Biochem Cell Biol. 2017 Jul;88:196.
doi: 10.1016/j.biocel.2017.06.003. Authors Irmgard Iminger-Finger 1 , Joanna Kargul 2 , Geoff …

Regenerative medicine and stem cells: Prometheus revisited

D Bouros, G Laurent - Respiration, 2012 - karger.com
The concept of tissue regeneration is not new and can be traced back to Greek mythology.
Prometheus stole fire from the Olympian gods for human use in order to advance civilization …

[HTML][HTML] Rac1 deletion causes thymic atrophy

L Hunziker, S Aznar Benitah, KM Braun, K Jensen… - PLoS …, 2011 - journals.plos.org
The thymic stroma supports T lymphocyte development and consists of an epithelium
maintained by thymic epithelial progenitors. The molecular pathways that govern epithelial …

[HTML][HTML] Antagonizing functions of BARD1 and its alternatively spliced variant BARD1δ in telomere stability

M Pilyugin, PA André, M Ratajska, A Kuzniacka… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Previous reports have shown that expression of BARD1δ, a deletion-bearing isoform of
BARD1, correlates with tumor aggressiveness and progression. We show that expression of …