Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome associated
with abnormal inflammatory immune responses of the lung to noxious particles and gases …

Chronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation of
the airways and progressive destruction of lung parenchyma, a process that in most cases is …

The first discovery that interleukin-4 (IL-4) is crucial in the development of allergic airway
inflammation originates from the early 1990s. Whereas initial studies in experimental animal …

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by chronic
airway inflammation. It is unclear if dendritic cells (DC) participate in this inflammatory …

The term severe refractory asthma (SRA) in adults applies to patients who remain difficult to
control despite extensive re-evaluation of diagnosis and management following an …

Indirect challenges act by causing the release of endogenous mediators that cause the
airway smooth muscle to contract. This is in contrast to the direct challenges where agonists …

Cigarette smoke (CS), the primary risk factor of chronic obstructive pulmonary disease
(COPD), leads to pulmonary inflammation through interleukin-1 receptor (IL-1R) I signalling …

Inflammation of the airways and lung parenchyma plays a major role in the pathogenesis of
chronic obstructive pulmonary disease. In the present study a murine model of tobacco …

Chronic obstructive pulmonary disease (COPD) is mainly caused by cigarette smoking, and
is characterized by an increase in inflammatory cells in the airways and pulmonary tissue …

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by progressive
inflammation in the airways and lungs combined with disturbed homeostatic functions of …