Importance Controversy remains about whether depression can be successfully managed
after acute coronary syndrome (ACS) and the costs and benefits of doing so. Objective To …

BACKGROUND: Atopy and asthma are commonly initiated during early life, and there is
increasing interest in the development of preventive treatments for at-risk children. However …

Introduction Improved nutrition is the major proven benefit of newborn screening
programmes for cystic fibrosis (CF) and is associated with better clinical outcomes. It was …

Background In school-aged children with cystic fibrosis (CF) structural lung damage
assessed using chest CT is associated with abnormal ventilation distribution. The primary …

Bacterial colonisation of the airways is associated with increased risk of childhood asthma.
Immunoglobulin (Ig) E against bacterial antigens has been reported in some asthmatics …

BACKGROUND: Current treatment strategies for asthma in teenagers derive primarily from
information on chronic disease in adults. More detailed understanding of risk factors related …

Importance Patients with acute coronary syndrome (ACS) and elevated depressive
symptoms are at increased risk for recurrent cardiovascular events and mortality, worse …

Background Posttraumatic stress disorder (PTSD) is a heterogeneous construct, and some
have suggested that PTSD triggered by acute coronary syndrome (ACS) may differ from …

Background There are substantial differences in the effects of blood pressure (BP)
medications in individual patients. Yet, the current standard approach to prescribing BP …

Background Nonadherence to study protocols reduces the generalizability, validity, and
statistical power of longitudinal studies. Purpose To determine whether an automated …