[HTML][HTML] A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults
PW Stacpoole, EC Wright… - … England Journal of …, 1992 - Mass Medical Soc
Background. Mortality is very high in lactic acidosis, and there is no satisfactory treatment
other than treatment of the underlying cause. Uncontrolled studies have suggested that …
other than treatment of the underlying cause. Uncontrolled studies have suggested that …
[HTML][HTML] Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial
AD Martin, BK Smith, PD Davenport, E Harman… - Critical care, 2011 - Springer
Introduction Most patients are readily liberated from mechanical ventilation (MV) support,
however, 10%-15% of patients experience failure to wean (FTW). FTW patients account for …
however, 10%-15% of patients experience failure to wean (FTW). FTW patients account for …
Treatment of lactic acidosis with dichloroacetate
PW Stacpoole, EM Harman, SH Curry… - … England Journal of …, 1983 - Mass Medical Soc
We administered dichloroacetate, which prevents or reverses hyperlactatemia in animals
and lowers plasma lactate levels in human beings, to 13 patients with lactic acidosis of …
and lowers plasma lactate levels in human beings, to 13 patients with lactic acidosis of …
Natural history and course of acquired lactic acidosis in adults
PW Stacpoole, EC Wright, TG Baumgartner… - The American journal of …, 1994 - Elsevier
Abstract study objective: To determine the pathogenesis and clinical course of lactic acidosis
in adults receiving standard medical care. design: Placebo arm of a 5-year prospective …
in adults receiving standard medical care. design: Placebo arm of a 5-year prospective …
The effect of weight loss on sleep-disordered breathing and oxygen desaturation in morbidly obese men
EM Harman, JW Wynne, AJ Block - Chest, 1982 - Elsevier
Four morbidly obese men who had been found to have significant sleep-disordered
breathing and oxygen desaturation were restudied after an average weight loss of 108 kg …
breathing and oxygen desaturation were restudied after an average weight loss of 108 kg …
Increased urinary excretion of LTE4 after exercise and attenuation of exercise-induced bronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist.
TF Reiss, JB Hill, E Harman, J Zhang, WK Tanaka… - Thorax, 1997 - thorax.bmj.com
BACKGROUND: A study was undertaken to determine whether montelukast, a new potent
cysteinyl leukotriene receptor antagonist, attenuates exercise-induced bronchoconstriction …
cysteinyl leukotriene receptor antagonist, attenuates exercise-induced bronchoconstriction …
Use of inspiratory muscle strength training to facilitate ventilator weaning: a series of 10 consecutive patients
AD Martin, PD Davenport, AC Franceschi, E Harman - Chest, 2002 - Elsevier
Background and purpose We instituted a low-repetition, high-intensity inspiratory muscle
strength training (IMST) program and progressively longer spontaneous breathing periods …
strength training (IMST) program and progressively longer spontaneous breathing periods …
Dichloroacetate in the treatment of lactic acidosis
PW STACPOOLE, AC LORENZ… - Annals of internal …, 1988 - acpjournals.org
An open, prospective evaluation of the effects of dichloroacetate on morbidity and survival
time was done in 29 pediatric and adult patients with lactic acidosis. Dichloroacetate was …
time was done in 29 pediatric and adult patients with lactic acidosis. Dichloroacetate was …
Complete remission of pulmonary spindle cell carcinoma after treatment with oral germanium sesquioxide
MG Mainwaring, C Poor, E Harman, DS Zander - Chest, 2000 - Elsevier
Spindle cell carcinoma (SCC) is a rare form of lung cancer representing 0.2 to 0.3% of all
primary pulmonary malignancies. Even with combined surgery, chemotherapy, and radiation …
primary pulmonary malignancies. Even with combined surgery, chemotherapy, and radiation …
Novel therapies in asthma: leukotriene antagonists, biologic agents, and beyond
ES Papierniak, DT Lowenthal… - American journal of …, 2013 - journals.lww.com
Asthma is one of the most common conditions seen in clinical practice and carries both a
significant disease burden in terms of patient morbidity and a high economic burden in both …
significant disease burden in terms of patient morbidity and a high economic burden in both …