Many studies have been published in the last 10 years on the efficacy and safety of
montelukast in asthma since this drug entered the market. Experimental studies, in vitro and …

Severe asthma affects about 10% of the population with asthma and is characterized by low
lung function and a high count of blood leukocytes, mainly eosinophils. Various definitions …

Background: The prognostic role of low sputum eosinophils in steroid-naïve, symptomatic
asthmatic patients is controversial. Aim: To verify whether low sputum eosinophils predict …

Background. Neutrophilic bronchial inflammation is a main feature of bronchiectasis, but not
much is known about its relationship with other disease features. Aim. To compare airway …

Background Mepolizumab (MEP) has been recently introduced to treat severe eosinophilic
asthma. Trials have demonstrated a significant effectiveness in this asthma phenotype. We …

Background. Asthma Control Test (ACT) is a simple tool for assessing the level of asthma
control in clinical practice, and it has been validated in comparison with a general clinical …

We investigated whether exposure to ozone (O3) 24 hours after an allergen challenge test
would increase airway eosinophilia induced by allergen in subjects with mild asthma with …

Objective To evaluate the potential determinants of forced expiratory volume in 1 s (FEV1)
decline in workers with occupational asthma (OA) still exposed to the causative agent. We …

Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a necrotizing vasculitis
that predominantly affects small-to medium-sized vessels. It is characterized by a wide …

Abstract Background Although general practitioners (GPs) are frequently the first healthcare
professionals whom asthma patients refer to for their symptoms, few studies have explored …