Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …

Sclerostin has been identified as an important regulator of bone homeostasis through
inhibition of the canonical Wnt-signaling pathway, and it is involved in the pathogenesis of …

Introduction: The number of cases of drug-resistant Mycobacterium tuberculosis, the
causative agent of tuberculosis (TB), has risen rapidly in recent years. This has led to the …

To evaluate these risks, we enrolled 200 patient-facing HCWs between March 26 and April
8, 2020, in SARS-CoV-2 Acquisition in Frontline Healthcare Workers—Evaluation to inform …

Management of high energy intra-articular fractures of the proximal tibia, associated with
marked soft-tissue trauma, can be challenging, requiring the combination of accurate …

Tuberculosis still remains a global health emergency, claiming 1.5 million lives in 2013. The
bacterium responsible for this disease, Mycobacterium tuberculosis (M. tb), has successfully …

From Allium stipitatum, three pyridine-N-oxide alkaloids (1− 3) possessing disulfide
functional groups were isolated. The structures of these natural products were elucidated by …

Background: Despite its limitations, citation analysis remains one of the best currently
available tools for quantifying the impact of articles. Bibliometric studies list the “best-sellers” …

Background Optimal therapy for anterior cruciate ligament (ACL) rupture in the paediatric
population still provokes controversy. Although conservative and operative treatments are …

Objectives New anti-mycobacterial entities with novel mechanisms of action are clinically
needed for treating resistant forms of tuberculosis. The purpose of this study was to evaluate …