Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

Obstructive sleep apnoea is a disease of increasing importance because of its
neurocognitive and cardiovascular sequelae. Abnormalities in the anatomy of the pharynx …

Considerable progress has been made over the last several decades in our understanding
of the pathophysiology of both central and obstructive sleep apnea. Central sleep apnea, in …

Background Obstructive sleep apnea is associated with an increased risk of cardiovascular
events; whether treatment with continuous positive airway pressure (CPAP) prevents major …

Background Long-term sleep deprivation is common in today's society. Recent experiments
have demonstrated that short-term sleep deprivation in healthy subjects results in adverse …

Rationale: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among
patients but have not been well characterized. Objectives: To define carefully the proportion …

Pharyngeal collapse in obstructive sleep apnea patients is likely a product of a sleep-related
decrement in pharyngeal dilator muscle activity superimposed upon abnormal airway …

Short-term sleep restriction results in impaired glucose tolerance. To test whether habitually
short sleep duration increases the risk of developing diabetes, we studied a cohort of 70,026 …

Physiologic studies suggest that sleep restriction has metabolic effects that predispose to
weight gain. The authors investigated the association between self-reported usual sleep …

We developed a short-length document that clearly delineates a prudent approach to and
criteria for reimbursement of positive airway pressure (PAP) costs for the treatment of …