Importance Mendelian randomization (MR) studies use genetic variation associated with
modifiable exposures to assess their possible causal relationship with outcomes and aim to …

Background Few pediatric cases of coronavirus disease 2019 (COVID-19) have been
reported and we know little about the epidemiology in children, although more is known …

Background—In the absence of previous international comparisons, we sought to
systematically evaluate, across time and participant age, the sex ratio in angina prevalence …

Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …

We expanded GWAS discovery for type 2 diabetes (T2D) by combining data from 898,130
European-descent individuals (9% cases), after imputation to high-density reference panels …

Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …

Genome-wide association (GWA) studies have identified multiple loci at which common
variants modestly but reproducibly influence risk of type 2 diabetes (T2D),,,,,,,,,,. Established …

By combining genome-wide association data from 8,130 individuals with type 2 diabetes
(T2D) and 38,987 controls of European descent and following up previously unidentified …

Here we conducted a large-scale genetic association analysis of educational attainment in a
sample of approximately 1.1 million individuals and identify 1,271 independent genome …

Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …