User profiles for "author:Christopher Brightling"
christopher brightlingProfessor Respiratory Medicine, University of Leicester Verified email at leicester.ac.uk Cited by 87756 |
Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes
HK Reddel, LB Bacharier, ED Bateman… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually
updated evidence-based strategy for asthma management and prevention, which can be …
updated evidence-based strategy for asthma management and prevention, which can be …
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs
J Bousquet, HJ Schünemann, B Samolinski… - Journal of Allergy and …, 2012 - Elsevier
Allergic rhinitis (AR) and asthma represent global health problems for all age groups.
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact …
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact …
Targeting TNF-α: a novel therapeutic approach for asthma
Approximately 5% to 10% of patients with asthma have severe disease that is refractory or
poorly responsive to inhaled corticosteroid therapy. These patients represent an important …
poorly responsive to inhaled corticosteroid therapy. These patients represent an important …
Effect of dexamethasone in hospitalized patients with COVID-19–preliminary report
ABSTRACT Background Coronavirus disease 2019 (COVID-19) is associated with diffuse
lung damage. Corticosteroids may modulate immune-mediated lung injury and reducing …
lung damage. Corticosteroids may modulate immune-mediated lung injury and reducing …
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …
Task Force, supported by the European Respiratory Society and American Thoracic Society …
Cluster analysis and clinical asthma phenotypes
Rationale: Heterogeneity in asthma expression is multidimensional, including variability in
clinical, physiologic, and pathologic parameters. Classification requires consideration of …
clinical, physiologic, and pathologic parameters. Classification requires consideration of …
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial
RH Green, CE Brightling, S McKenna, B Hargadon… - The Lancet, 2002 - thelancet.com
Background Treatment decisions in asthma are based on assessments of symptoms and
simple measures of lung function, which do not relate closely to underlying eosinophilic …
simple measures of lung function, which do not relate closely to underlying eosinophilic …
[HTML][HTML] Mepolizumab and exacerbations of refractory eosinophilic asthma
P Haldar, CE Brightling, B Hargadon… - New England journal …, 2009 - Mass Medical Soc
Background Exacerbations of asthma are associated with substantial morbidity and mortality
and with considerable use of health care resources. Preventing exacerbations remains an …
and with considerable use of health care resources. Preventing exacerbations remains an …
[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
RA Evans, H McAuley, EM Harrison… - The Lancet …, 2021 - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …
hospitalisation with acute disease is not well understood. The aim of this study was to …
[HTML][HTML] Mast-cell infiltration of airway smooth muscle in asthma
CE Brightling, P Bradding, FA Symon… - … England Journal of …, 2002 - Mass Medical Soc
Background Asthma and eosinophilic bronchitis are characterized by similar inflammatory
infiltrates in the submucosa of the lower airway. However, eosinophilic bronchitis differs from …
infiltrates in the submucosa of the lower airway. However, eosinophilic bronchitis differs from …