Silicosis

CC Leung, ITS Yu, W Chen - The Lancet, 2012 - thelancet.com
Silicosis is a fibrotic lung disease caused by inhalation of free crystalline silicon dioxide or
silica. Occupational exposure to respirable crystalline silica dust particles occurs in many …

Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis

N Ahmad, SD Ahuja, OW Akkerman, JWC Alffenaar… - The Lancet, 2018 - thelancet.com
Background Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed
to estimate the association of treatment success and death with the use of individual drugs …

Antituberculosis drugs and hepatotoxicity

WW Yew, CC Leung - Respirology, 2006 - Wiley Online Library
Isoniazid, pyrazinamide and rifampicin have hepatotoxic potential, and can lead to such
reactions during antituberculosis chemotherapy. Most of the hepatotoxic reactions are dose …

Wearing face masks in the community during the COVID-19 pandemic: altruism and solidarity

KK Cheng, TH Lam, CC Leung - The Lancet, 2022 - thelancet.com
As the coronavirus disease 2019 (COVID-19) pandemic progresses, one debate relates to
the use of face masks by individuals in the community. We previously highlighted some …

[HTML][HTML] Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients

SD Ahuja, D Ashkin, M Avendano, R Banerjee… - 2012 - journals.plos.org
Background Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic,
expensive, and has generally poor outcomes. We undertook an individual patient data meta …

[PDF][PDF] Mass masking in the COVID-19 epidemic: people need guidance

CC Leung, TH Lam, KK Cheng - Lancet, 2020 - aphn.org
As the spread of coronavirus disease 2019 (COVID-19) outside China is accelerating, we
urge policy makers to reconsider the role of masking. The non-specific symptoms at early …

Outcomes of patients with multidrug-resistant pulmonary tuberculosis treated with ofloxacin/levofloxacin-containing regimens

WW Yew, CK Chan, CH Chau, CM Tam, CC Leung… - Chest, 2000 - Elsevier
Objective To analyze outcomes of patients with multidrug-resistant tuberculosis (MDR-TB)
treated with ofloxacin/levofloxacin-containing regimens. Materials and methods From …

Antituberculosis drug-related liver dysfunction in chronic hepatitis B infection

WM Wong, PC Wu, MF Yuen, CC Cheng, WW Yew… - Hepatology, 2000 - journals.lww.com
Liver toxicity is a common side effect of antituberculosis (anti-TB) drugs. We studied the
differences in liver dysfunction observed during anti-TB treatment between hepatitis B virus …

[HTML][HTML] Epidemic and pandemic viral infections: impact on tuberculosis and the lung: A consensus by the World Association for Infectious Diseases and …

CWM Ong, GB Migliori, M Raviglione… - European …, 2020 - Eur Respiratory Soc
Major epidemics, including some that qualify as pandemics, such as severe acute
respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A …

[HTML][HTML] CISH and Susceptibility to Infectious Diseases

CC Khor, FO Vannberg, SJ Chapman… - … England Journal of …, 2010 - Mass Medical Soc
Background The interleukin-2–mediated immune response is critical for host defense
against infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein …