Background Multiple imputation has become very popular as a general-purpose method for
handling missing data. The validity of multiple-imputation-based analyses relies on the use …

Importance Although multiple cross-sectional and longitudinal studies have established that
sleep problems and behavioral difficulties are associated in children, the directionality of this …

Pneumococcal disease is a leading cause of childhood mortality, globally. The
pneumococcal conjugate vaccine (PCV) has been introduced to many countries worldwide …

Poor participant engagement undermines individual and public health benefits of early
intervention programs. This study assessed the extent to which three types of engagement …

Background: The prevalence of social media makes it a potential alternative to traditional
offline methods of recruiting and engaging participants in health research. Despite …

Background The indirect effects of pneumococcal conjugate vaccines (PCVs) are mediated
through reductions in carriage of vaccine serotypes. Data on PCVs in Asia and the Pacific …

Pneumococcal disease is a major contributor to global childhood morbidity and mortality
and is more common in low-and middle-income countries (LMICs) than in high-income …

Pneumococcal carriage is a prerequisite for disease, and underpins herd protection
provided by pneumococcal conjugate vaccines (PCVs). There are few data on the impact of …

Abstract Objectives Nasopharyngeal carriage of Streptococcus pneumoniae underpins
disease development and transmission. This study was performed to examine …

Multiple imputation is a recommended method for handling incomplete data problems. One
of the barriers to its successful use is the breakdown of the multiple imputation procedure …