[HTML][HTML] Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland

A da Silva Filipe, JG Shepherd, T Williams… - Nature …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) was first diagnosed in Scotland on 1 March
2020. During the first month of the outbreak, 2,641 cases of COVID-19 led to 1,832 hospital …

The association between SARS-CoV-2 RT-PCR cycle threshold and mortality in a community cohort

R Waudby-West, BJ Parcell… - European …, 2021 - Eur Respiratory Soc
A coronavirus disease 2019 (COVID-19) diagnosis is widely made by the use of reverse
transcription polymerase chain reaction (RT-PCR) testing for severe acute respiratory …

[HTML][HTML] Pseudomonas aeruginosa intensive care unit outbreak: winnowing of transmissions with molecular and genomic typing

BJ Parcell, K Oravcova, M Pinheiro, MTG Holden… - Journal of Hospital …, 2018 - Elsevier
Background Pseudomonas aeruginosa healthcare outbreaks can be time consuming and
difficult to investigate. Guidance does not specify which typing technique is most practical for …

[HTML][HTML] Clinical perspectives in integrating whole-genome sequencing into the investigation of healthcare and public health outbreaks–hype or help?

BJ Parcell, SH Gillespie, KA Pettigrew… - Journal of Hospital …, 2021 - Elsevier
Outbreaks pose a significant patient safety risk as well as being costly and time consuming
to investigate. The implementation of targeted infection prevention and control (IPC) …

[HTML][HTML] The protective effect of SARS-CoV-2 antibodies in Scottish healthcare workers

H Abo-Leyah, S Gallant, D Cassidy… - ERJ Open …, 2021 - Eur Respiratory Soc
Background Healthcare workers (HCWs) are believed to be at increased risk of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. It is not known to what extent …

[HTML][HTML] Modulation of multidrug-resistant clone success in Escherichia coli populations: a longitudinal, multi-country, genomic and antibiotic usage cohort study

AK Pöntinen, RA Gladstone, H Pesonen… - The Lancet …, 2024 - thelancet.com
Background The effect of antibiotic usage on the success of multidrug-resistant (MDR)
clones in a population remains unclear. With this genomics-based molecular epidemiology …

Drive-through testing for SARS-CoV-2 in symptomatic health and social care workers and household members: an observational cohort study

BJ Parcell, K Brechin, S Allstaff, M Park, W Third… - Thorax, 2020 - thorax.bmj.com
The requirement for health and social care workers to self-isolate when they or their
household contacts develop symptoms consistent with severe acute respiratory syndrome …

[HTML][HTML] Clinical and Genomic Evolution of Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections over Two Time Periods at a Tertiary Care Hospital …

A Manesh, C Shankar, MM George, DS Jasrotia… - Infectious Diseases and …, 2023 - Springer
Introduction The objective of this study was to examine the evolution of carbapenem-
resistant Klebsiella pneumoniae (CRKp) infections and their impact at a tertiary care hospital …

First report of an astrovirus type 5 gastroenteritis outbreak in a residential elderly care home identified by sequencing

AA Jarchow-Macdonald, S Halley, D Chandler… - Journal of Clinical …, 2015 - Elsevier
Background This is the report of an outbreak of human astrovirus type 5 gastroenteritis that
occurred in a residential care home for older people in June 2013 in Tayside, Scotland, and …

[HTML][HTML] Dual β-lactam combination therapy for multi-drug resistant Pseudomonas aeruginosa infection: enhanced efficacy in vivo and comparison with …

T Siriyong, RM Murray, LE Bidgood, SA Young… - Scientific Reports, 2019 - nature.com
The aim of the study was to determine the efficacy of dual β-lactam combination treatments
derived from eight approved drugs against Galleria mellonella larvae infected with MDR …