Human breast milk: A review on its composition and bioactivity

NJ Andreas, B Kampmann, KM Le-Doare - Early human development, 2015 - Elsevier
Breast milk is the perfect nutrition for infants, a result of millions of years of evolution, finely
attuning it to the requirements of the infant. Breast milk contains many complex proteins …

Paediatric tuberculosis

SM Newton, AJ Brent, S Anderson… - The Lancet infectious …, 2008 - thelancet.com
Tuberculosis continues to cause an unacceptably high toll of disease and death among
children worldwide, particularly in the wake of the HIV epidemic. Increased international …

[PDF][PDF] Protecting the newborn and young infant from infectious diseases: lessons from immune ontogeny

TR Kollmann, B Kampmann, SK Mazmanian… - Immunity, 2017 - cell.com
Infections in the first year of life are common and often severe. The newborn host
demonstrates both quantitative and qualitative differences to the adult in nearly all aspects of …

Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants

B Kampmann, SA Madhi, I Munjal… - … England Journal of …, 2023 - Mass Medical Soc
Background Whether vaccination during pregnancy could reduce the burden of respiratory
syncytial virus (RSV)–associated lower respiratory tract illness in newborns and infants is …

The risk of tuberculosis related to tumour necrosis factor antagonist therapies: a TBNET consensus statement

I Solovic, M Sester, JJ Gomez-Reino, HL Rieder… - 2010 - Eur Respiratory Soc
Anti-tumour necrosis factor (TNF) monoclonal antibodies or soluble TNF receptors have
become an invaluable treatment against chronic inflammatory diseases, such as rheumatoid …

A single dose of vitamin D enhances immunity to mycobacteria

AR Martineau, RJ Wilkinson, KA Wilkinson… - American journal of …, 2007 - atsjournals.org
Rationale: Vitamin D was used to treat tuberculosis (TB) in the preantibiotic era. Prospective
studies to evaluate the effect of vitamin D supplementation on antimycobacterial immunity …

IFN-γ-and TNF-independent vitamin D-inducible human suppression of mycobacteria: the role of cathelicidin LL-37

AR Martineau, KA Wilkinson, SM Newton… - The Journal of …, 2007 - journals.aai.org
Vitamin D deficiency is associated with susceptibility to tuberculosis, and its biologically
active metabolite, 1α, 25 dihydroxyvitamin D 3 (1α, 25 (OH) 2 D 3), has pleiotropic immune …

[HTML][HTML] Neutrophil-mediated innate immune resistance to mycobacteria

AR Martineau, SM Newton… - The Journal of …, 2007 - Am Soc Clin Investig
Neutrophils contain antimicrobial peptides with antituberculous activity, but their contribution
to immune resistance to tuberculosis (TB) infection has not been previously investigated to …

Management of patients with multidrug-resistant/extensively drug-resistant tuberculosis in Europe: a TBNET consensus statement

C Lange, I Abubakar, JWC Alffenaar, G Bothamley… - 2014 - Eur Respiratory Soc
The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR)
tuberculosis (TB) substantially challenges TB control, especially in the European Region of …

Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an …

SM Graham, T Ahmed, F Amanullah… - Journal of Infectious …, 2012 - academic.oup.com
There is a critical need for improved diagnosis of tuberculosis in children, particularly in
young children with intrathoracic disease as this represents the most common type of …