Cyanide contamination of the puyango-tumbes river caused by artisanal gold mining in Portovelo-Zaruma, Ecuador

BG Marshall, MM Veiga, HAM da Silva… - Current Environmental …, 2020 - Springer
Abstract Purpose of Review To examine cyanide (CN-) contamination of a large river in
southeastern Ecuador that has been severely impacted by the indiscriminate discharge of …

Evidence of reduced mercury loss and increased use of cyanidation at gold processing centers in southern Ecuador

AO Gonçalves, BG Marshall, RJ Kaplan… - Journal of Cleaner …, 2017 - Elsevier
Due to the strong price of gold, the number and capacity of gold processing centers in
Portovelo-Zaruma in southern Ecuador have increased considerably in recent years. In turn …

Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

MG Jones, OG Andriotis, JJW Roberts, K Lunn, VJ Tear… - Elife, 2018 - elifesciences.org
Matrix stiffening with downstream activation of mechanosensitive pathways is strongly
implicated in progressive fibrosis; however, pathologic changes in extracellular matrix …

[HTML][HTML] Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis

C Hill, J Li, D Liu, F Conforti, CJ Brereton, L Yao… - Cell death & …, 2019 - nature.com
Idiopathic pulmonary fibrosis (IPF), the prototypic progressive fibrotic interstitial lung
disease, is thought to be a consequence of repetitive micro-injuries to an ageing …

[HTML][HTML] Paracrine signalling during ZEB1-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in lung fibrosis

L Yao, F Conforti, C Hill, J Bell, L Drawater… - Cell Death & …, 2019 - nature.com
The contribution of epithelial–mesenchymal transition (EMT) to human lung fibrogenesis is
controversial. Here we provide evidence that ZEB1-mediated EMT in human alveolar …

[HTML][HTML] Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis

MG Jones, A Fabre, P Schneider, F Cinetto, G Sgalla… - JCI insight, 2016 - ncbi.nlm.nih.gov
In idiopathic pulmonary fibrosis (IPF), the fibroblast focus is a key histological feature
representing active fibroproliferation. On standard 2D pathologic examination, fibroblast foci …

The Colombian artisanal mining sector: Formalization is a heavy burden

MM Veiga, BG Marshall - The Extractive Industries and Society, 2019 - Elsevier
Abstract The Ministry of Mines and Energy (MME) in Colombia has the potential to be the
most pro-active government ministry in the world to deal with the problem of formalization of …

Formalization of artisanal miners: stop the train, we need to get off!

BG Marshall, MM Veiga - The Extractive Industries and Society, 2017 - Elsevier
The formalization of artisanal miners, mainly gold miners, in developing countries continues
unabated, although the results have not been fruitful. Due to the strong price of gold and …

Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis

CJ Brereton, L Yao, ER Davies, Y Zhou, M Vukmirovic… - Elife, 2022 - elifesciences.org
Extracellular matrix (ECM) stiffening with downstream activation of mechanosensitive
pathways is strongly implicated in fibrosis. We previously reported that altered collagen …

Dissection of the host-pathogen interaction in human tuberculosis using a bioengineered 3-dimensional model

LB Tezera, MK Bielecka, A Chancellor, MT Reichmann… - Elife, 2017 - elifesciences.org
Cell biology differs between traditional cell culture and 3-dimensional (3-D) systems, and is
modulated by the extracellular matrix. Experimentation in 3-D presents challenges …