Specialised CF care has led to a dramatic improvement in survival in CF: in the last four
decades, well above what was seen in the general population over the same period. With …

Developments in managing CF continue to drive dramatic improvements in survival. As
newborn screening rolls-out across Europe, CF centres are increasingly caring for cohorts of …

Objective: To determine the effects of environmental tobacco smoke (ETS) exposure on birth
outcomes. Design: A systematic review and meta-analysis was performed in accordance …

The views and recommendations made in this document do not represent the official
position of any publisher or professional medical society. This document has not been …

Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can
cause chronic pulmonary infection, particularly in individuals with pre-existing inflammatory …

Background Respiratory tract infections with Pseudomonas aeruginosa occur in most
people with cystic fibrosis (CF). Established chronic P aeruginosa infection is virtually …

Objective To examine compliance with mandatory reporting of summary clinical trial results
(within one year of completion of trial) on ClinicalTrials. gov for studies that fall under the …

Background Attacks of wheezing induced by upper respiratory viral infections are common
in preschool children between the ages of 10 months and 6 years. A short course of oral …

There is wide agreement on the benefits of NBS for CF in terms of lowered disease severity,
decreased burden of care, and reduced costs. Risks are mainly associated with disclosure …

Prediction models aim to use available data to predict a health state or outcome that has not
yet been observed. Prediction is primarily relevant to clinical practice, but is also used in …