User profiles for "author:Adnan Custovic"

Adnan Custovic

Professor of Paediatric Allergy
Verified email at imperial.ac.uk
Cited by 58960

Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome

J Lötvall, CA Akdis, LB Bacharier, L Bjermer… - Journal of Allergy and …, 2011 - Elsevier
It is increasingly clear that asthma is a complex disease made up of number of disease
variants with different underlying pathophysiologies. Limited knowledge of the mechanisms …

Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach

PLP Brand, E Baraldi, H Bisgaard… - European …, 2008 - Eur Respiratory Soc
There is poor agreement on definitions of different phenotypes of preschool wheezing
disorders. The present Task Force proposes to use the terms episodic (viral) wheeze to …

[HTML][HTML] Epidemiology of asthma in children and adults

SC Dharmage, JL Perret, A Custovic - Frontiers in pediatrics, 2019 - frontiersin.org
Asthma is a globally significant non-communicable disease with major public health
consequences for both children and adults, including high morbidity, and mortality in severe …

After asthma: redefining airways diseases

ID Pavord, R Beasley, A Agusti, GP Anderson, E Bel… - The Lancet, 2018 - thelancet.com
Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …

International consensus on (ICON) pediatric asthma

NG Papadopoulos, H Arakawa, KH Carlsen… - Allergy, 2012 - Wiley Online Library
Asthma is the most common chronic lower respiratory disease in childhood throughout the
world. Several guidelines and/or consensus documents are available to support medical …

Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs

J Bousquet, HJ Schünemann, B Samolinski… - Journal of Allergy and …, 2012 - Elsevier
Allergic rhinitis (AR) and asthma represent global health problems for all age groups.
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact …

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

K Bønnelykke, P Sleiman, K Nielsen, E Kreiner-Møller… - Nature …, 2014 - nature.com
Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome …

Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children

CS Murray, G Poletti, T Kebadze, J Morris, A Woodcock… - Thorax, 2006 - thorax.bmj.com
Background: Asthma exacerbation is the most common cause of hospital admission in
children. A study was undertaken to investigate the importance of allergen exposure in …

International consensus statement on allergy and rhinology: allergic rhinitis

SK Wise, SY Lin, E Toskala, RR Orlandi… - International forum of …, 2018 - Wiley Online Library
Background Critical examination of the quality and validity of available allergic rhinitis (AR)
literature is necessary to improve understanding and to appropriately translate this …

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

JS Ried, J Li, XB Zuo, XD Zheng, XY Yin, LD Sun… - Nature …, 2015 - nature.com
Genetic association studies have identified 21 loci associated with atopic dermatitis risk
predominantly in populations of European ancestry. To identify further susceptibility loci for …