Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …

The Alpha Magnetic Spectrometer (AMS) was flown on the space shuttle Discovery during
flight STS-91 (June 1998) in a 51.7° orbit at altitudes between 320 and 390 km. A search for …

Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of
morbidity, mortality, and resource use worldwide. The goal of this Official American Thoracic …

Background In some patients with chronic obstructive pulmonary disease (COPD), type 2
inflammation may increase exacerbation risk and may be indicated by elevated blood …

Rhinoviruses are the major cause of asthma exacerbations, and asthmatics have increased
susceptibility to rhinovirus and risk of invasive bacterial infections. Here we show deficient …

Background Respiratory syncytial virus (RSV) is an important cause of acute respiratory
infection, lower respiratory tract disease, clinical complications, and death in older adults …

Rationale: Severe exacerbations of chronic obstructive pulmonary disease (COPD) are
major causes of health care costs mostly related to hospitalization. The role of infections in …

Background Eosinophilia is associated with worsening asthma severity and decreased lung
function, with increased exacerbation frequency. We assessed the safety and efficacy of …

This document provides clinical recommendations for treatment of chronic obstructive
pulmonary disease (COPD) exacerbations. Comprehensive evidence syntheses, including …

To determine whether patients with fixed airflow obstruction have distinct pathologic and
functional characteristics depending on a history of either asthma or chronic obstructive …