The use of inhaled aerosolized prostacyclin (IAP) in the treatment of pulmonary hypertension secondary to pulmonary embolism

Intensive Care Med. 1996 Apr;22(4):353-5. doi: 10.1007/BF01700458.

Abstract

Objective: To describe the use of inhaled aerosolized prostacyclin (IAP) in a patient with life-threatening pulmonary hypertension secondary to pulmonary embolism and to discuss the possible use of inhaled prostacyclin in the management of pulmonary embolism.

Design: Case report.

Setting: Intensive care unit of a university teaching hospital.

Patients: One patient with severe pulmonary hypertension secondary to acute-on-chronic pulmonary embolism.

Interventions: Conventional medical management of massive pulmonary embolism and inhaled aerosolized prostacyclin (IAP).

Measurements and results: Description of clinical course, haemodynamic data and gas exchange data.

Conclusions: We describe a patient with massive pulmonary embolism for whom the addition of IAP to his therapy appeared to result in a transient improvement in pulmonary haemodynamics and gas exchange.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Aerosols
  • Aged
  • Epoprostenol / therapeutic use*
  • Humans
  • Hypertension, Pulmonary / drug therapy*
  • Hypertension, Pulmonary / etiology
  • Male
  • Pulmonary Embolism / complications*
  • Ventricular Dysfunction, Right / etiology

Substances

  • Aerosols
  • Epoprostenol