Aeroallergen sensitization can occur during fetal life

Int Arch Allergy Immunol. 1993;102(3):301-3. doi: 10.1159/000236541.

Abstract

Umbilical cord blood lymphocytes showed consistent proliferation in response to Dermatophagoides group I (Der p I) and occasionally even to Lolium group I (Lol p I) allergen. These data suggest sensitization in utero of T cells due to inhalation of these allergens by the mother during pregnancy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aerosols
  • Allergens*
  • Antigens, Dermatophagoides
  • Antigens, Plant
  • Fetal Blood
  • Glycoproteins / administration & dosage*
  • Glycoproteins / immunology
  • Humans
  • Hypersensitivity / embryology*
  • Immunologic Memory
  • Infant, Newborn
  • Lymphocyte Activation
  • Lymphocytes / immunology*
  • Plant Proteins / administration & dosage*
  • Plant Proteins / immunology

Substances

  • Aerosols
  • Allergens
  • Antigens, Dermatophagoides
  • Antigens, Plant
  • Glycoproteins
  • Lol p I protein, Lolium perenne
  • Plant Proteins