Immunoperoxidase localization of factor VIII in angiosarcomas

Arch Pathol Lab Med. 1982 Oct;106(10):515-6.

Abstract

Factor VIII-related antigen was studied in 28 cases of angiosarcoma from different sites by means of the immunoperoxidase technique. Positive immunostaining was observed in 23 cases. Five cases composed preponderantly of solid areas, with little vasoformative activity, showed negative immunostaining. This technique is of value in diagnosing tumors of endothelial origin.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens / analysis*
  • Cytoplasm / immunology
  • Endothelium / immunology
  • Factor VII / immunology*
  • Factor VIII / analysis
  • Factor VIII / immunology*
  • Hemangiosarcoma / immunology*
  • Histocytochemistry
  • Humans
  • Immunoenzyme Techniques
  • Lymphangioma / immunology
  • von Willebrand Factor

Substances

  • Antigens
  • von Willebrand Factor
  • Factor VII
  • Factor VIII