A place for ipratropium bromide in the treatment of severe acute asthma

Br J Dis Chest. 1985 Oct;79(4):374-8. doi: 10.1016/0007-0971(85)90071-3.

Abstract

Twenty-four consecutive patients admitted to hospital with severe acute asthma were studied. Eleven were given 10 mg salbutamol by nebulizer followed 2 hours later by 500 micrograms of nebulized ipratropium bromide. These patients had a greater response in PEFR than 13 patients given two doses of 10 mg salbutamol 2 hours apart.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Aged
  • Albuterol / therapeutic use
  • Asthma / drug therapy*
  • Atropine Derivatives / therapeutic use*
  • Clinical Trials as Topic
  • Double-Blind Method
  • Drug Therapy, Combination
  • Female
  • Humans
  • Ipratropium / therapeutic use*
  • Male
  • Middle Aged

Substances

  • Atropine Derivatives
  • Ipratropium
  • Albuterol