The Asthma-COPD Overlap Syndrome

N Engl J Med. 2015 Sep 24;373(13):1241-9. doi: 10.1056/NEJMra1411863.

Abstract

Although in textbooks asthma and chronic obstructive pulmonary disease (COPD) are viewed as distinct disorders, there is increasing awareness that many patients have features of both. This article reviews the asthma-COPD overlap syndrome.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adrenergic beta-Agonists / therapeutic use
  • Airway Obstruction / drug therapy
  • Airway Obstruction / etiology
  • Asthma / complications*
  • Asthma / diagnosis
  • Asthma / drug therapy
  • Bronchial Hyperreactivity / diagnosis
  • Bronchial Hyperreactivity / etiology
  • Eosinophils
  • Glucocorticoids / therapeutic use
  • Humans
  • Inflammation
  • Muscarinic Antagonists / therapeutic use
  • Pulmonary Disease, Chronic Obstructive / complications*
  • Pulmonary Disease, Chronic Obstructive / diagnosis
  • Pulmonary Disease, Chronic Obstructive / drug therapy

Substances

  • Adrenergic beta-Agonists
  • Glucocorticoids
  • Muscarinic Antagonists