Allergy screening with Phadiatop and CAP Phadiatop in combination with a questionnaire in adults with asthma and rhinitis

Allergy. 1990 May;45(4):285-92. doi: 10.1111/j.1398-9995.1990.tb00497.x.

Abstract

The efficiency of the new screening tests for atopy, Phadiatop and CAP Phadiatop, was studied by comparing their results with a clinical diagnosis of atopy in 100 consecutive adults with asthma and/or rhinitis. Further, the diagnostic efficiency of a combination of Phadiatop and a few standardized questions was studied. The Phadiatop was found to have a specificity of 0.98, and a sensitivity of 0.92 and the CAP Phadiatop a specificity of 0.94 and a sensitivity of 0.96. When the Phadiatop was combined with a few questions, a sensitivity of 1.00 was achieved. It is concluded that Phadiatop and CAP Phadiatop have a higher diagnostic precision than other hitherto used methods for screening of atopic allergy. The place of Phadiatop in a diagnostic flow chart is suggested.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Allergens / immunology
  • Asthma / immunology*
  • Female
  • Humans
  • Hypersensitivity, Immediate / diagnosis
  • Immunoglobulin E / immunology
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Radioimmunoassay / methods*
  • Radioimmunosorbent Test / methods*
  • Rhinitis / immunology*
  • Skin Tests
  • Surveys and Questionnaires

Substances

  • Allergens
  • Immunoglobulin E