Abstract
A wide variety of stimuli induce the inflammasome, but little is known about its role in immune protection against viruses. In this issue of Immunity, Allen et al. (2009) and Thomas et al. (2009) describe a critical role for NLRP3 induction of the inflammasome and protection against influenza virus infection.
MeSH terms
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Animals
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Carrier Proteins / genetics
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Carrier Proteins / immunology*
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Humans
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Influenza A virus / immunology*
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Monocytes / immunology
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NLR Family, Pyrin Domain-Containing 3 Protein
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Neutrophils / immunology
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Signal Transduction*
Substances
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Carrier Proteins
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NLR Family, Pyrin Domain-Containing 3 Protein
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NLRP3 protein, human