Nasal provocation test with lysine acetylsalicylate in aspirin-sensitive patients

Ann Allergy. 1991 Jul;67(1):60-2.

Abstract

The authors have studied nasal provocation testing (NPT) with aspirin in 45 aspirin-sensitive patients (40 affected by nasal polyposis) and in 38 aspirin-tolerant patients (27 affected by nasal polyposis). The test was positive in 37.7% of aspirin-intolerant subjects, but only in 7.9% of subjects in the control group (P less than .01).

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Analgesics / adverse effects*
  • Aspirin / adverse effects*
  • Aspirin / analogs & derivatives*
  • Drug Hypersensitivity / diagnosis*
  • Drug Hypersensitivity / pathology
  • Female
  • Humans
  • Lysine / adverse effects
  • Lysine / analogs & derivatives*
  • Male
  • Middle Aged
  • Nasal Mucosa / pathology
  • Nasal Provocation Tests*

Substances

  • Analgesics
  • Lysine
  • Aspirin
  • acetylsalicylic acid lysinate