Abstract
A retrospective review of medical records for all pediatric parapneumonic empyema (PPE) patients admitted to our hospital from 1996 to 2006 revealed that PPE increased 5-fold in the post-heptavalent pneumococcal conjugate vaccine (PCV7) period (2001-2005) relative to the pre-PCV7 period (1996-2000), from 13 cases to 65. Most of this increase was associated with culture-negative empyema, which accounted for 61% of all post-2000 cases; 19% was culture-positive pneumococcal empyema. Our analysis indicates that non-PCV7 serotypes became more prevalent at our institution after introduction of the vaccine.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Bacteremia / epidemiology
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Bacteremia / microbiology
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Bacteremia / prevention & control
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Child
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Child, Preschool
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Empyema, Pleural / epidemiology*
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Empyema, Pleural / microbiology
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Heptavalent Pneumococcal Conjugate Vaccine
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Humans
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Incidence
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Infant
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Infant, Newborn
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Meningitis, Pneumococcal / epidemiology
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Meningitis, Pneumococcal / microbiology
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Meningitis, Pneumococcal / prevention & control
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Meningococcal Vaccines*
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Pneumococcal Infections / epidemiology*
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Pneumococcal Infections / microbiology
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Pneumococcal Infections / prevention & control
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Pneumococcal Vaccines*
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Pneumonia, Pneumococcal / epidemiology
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Pneumonia, Pneumococcal / microbiology
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Pneumonia, Pneumococcal / prevention & control
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Retrospective Studies
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Serotyping
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Staphylococcal Infections / epidemiology
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Staphylococcal Infections / microbiology
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Staphylococcus aureus / isolation & purification
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Streptococcus pneumoniae / classification
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Streptococcus pneumoniae / isolation & purification
Substances
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Heptavalent Pneumococcal Conjugate Vaccine
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Meningococcal Vaccines
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Pneumococcal Vaccines