[A follow-up study of the lung function and the chest CT changes in medical staff with severe acute respiratory syndrome in Beijing]

Zhonghua Jie He He Hu Xi Za Zhi. 2005 Jan;28(1):10-2.
[Article in Chinese]

Abstract

Objective: To analyze the lung function and radiological changes in rehabilitating severe acute respiratory syndrome (SARS) patients of medical staff in Beijing.

Methods: Follow-up lung function tests and chest high-resolution computerized tomography (HRCT) were performed in medical staff with SARS from Dec. 2003 to Feb. 2004.

Results: Thirty-one (7.64%) of 406 patients showed abnormal ventilatory function, while 165 of 404 patients showed diffusing abnormality. Of the 434 patients who had received HRCT scans, 151 (34.79%) showed abnormalities including subpleural and basal ground-glass and reticular attenuation, nodular septal thickening and bronchiectasis. Of the 395 patients who had received both lung function test and HRCT scanning, 55 (13.92%) had abnormalities both in the lung function and HRCT. The decrease in diffusing capacity in patients with HRCT changes was more significant than those without HRCT changes.

Conclusions: Lung function and lung imaging were abnormal in some patients with SARS after recovery. It is suggested that the lung damage is chronic, and follow-up is needed.

MeSH terms

  • Adult
  • China
  • Female
  • Follow-Up Studies
  • Humans
  • Lung / physiopathology*
  • Male
  • Medical Staff, Hospital*
  • Middle Aged
  • Pulmonary Diffusing Capacity
  • Radiography, Thoracic*
  • Respiratory Function Tests
  • Severe Acute Respiratory Syndrome / diagnostic imaging*
  • Severe Acute Respiratory Syndrome / physiopathology
  • Tomography, X-Ray Computed