A randomised trial of single-dose radiotherapy to prevent procedure tract metastasis by malignant mesothelioma

S Bydder; M Phillips; D J Joseph; F Cameron; N A Spry; Y DeMelker; A W Musk

doi:10.1038/sj.bjc.6601957

A randomised trial of single-dose radiotherapy to prevent procedure tract metastasis by malignant mesothelioma

Br J Cancer. 2004 Jul 5;91(1):9-10. doi: 10.1038/sj.bjc.6601957.

Authors

S Bydder¹, M Phillips, D J Joseph, F Cameron, N A Spry, Y DeMelker, A W Musk

Affiliation

¹ Department of Radiation Oncology, Sir Charles Gairdner Hospital, Hospital Avenue, Perth, Nedlands, WA 6009, Australia. sean.bydder@health.wa.gov.au

Abstract

A single 9-MeV electron treatment, following invasive thoracic procedures in patients with malignant pleural mesothelioma, was examined. In all, 58 sites were randomised to prophylactic radiotherapy or not. There was no statistically significant difference in tract metastasis. A single 10-Gy treatment with 9-MeV electrons appears ineffective.

Publication types

Clinical Trial
Randomized Controlled Trial

MeSH terms

Aged
Aged, 80 and over
Electrons / therapeutic use
Female
Humans
Male
Mesothelioma / radiotherapy*
Mesothelioma / secondary*
Mesothelioma / surgery
Middle Aged
Neoplasm Metastasis / prevention & control*
Neoplastic Cells, Circulating*
Pleural Neoplasms / pathology*
Pleural Neoplasms / radiotherapy*
Pleural Neoplasms / surgery
Postoperative Complications / prevention & control*
Radiotherapy Dosage
Treatment Outcome