Abstract
Since the Swedish Twin Registry was first established in the late 1950s to study the importance of smoking and alcohol consumption on cancer and cardiovascular diseases, it has been expanded and updated on several occasions. The focus has similarly broadened to most common complex diseases. The content of the database is described, ongoing projects based on the registry are summarized, and we review some of the principal findings on aging, cancer and cardiovascular disease that have come from the registry. Ongoing efforts and future plans for the STR are discussed. Among others, we plan blood collection and genotyping to study the genetic bases of complex diseases, a first contact ever with the cohorts born after 1958, and in-depth studies of selected diseases, such as Parkinson's disease and chronic fatigue syndrome.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Alcohol Drinking / adverse effects
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Cardiovascular Diseases / epidemiology
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Cardiovascular Diseases / genetics
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Databases, Factual* / statistics & numerical data
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Databases, Factual* / trends
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Diseases in Twins / epidemiology*
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Diseases in Twins / genetics*
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Fatigue Syndrome, Chronic / epidemiology
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Fatigue Syndrome, Chronic / genetics
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Female
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Forecasting
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Gene Library
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Genotype
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Humans
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Male
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Neoplasms / epidemiology
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Neoplasms / genetics
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Parkinson Disease / epidemiology
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Parkinson Disease / genetics
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Registries* / statistics & numerical data
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Smoking / adverse effects
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Sweden / epidemiology
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Twin Studies as Topic / methods*
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Twin Studies as Topic / statistics & numerical data
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Twin Studies as Topic / trends
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Twins* / genetics
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Twins* / psychology
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Twins* / statistics & numerical data