Can retinoic acid ameliorate the physiologic and morphologic effects of elastase instillation in the rat?

Chest. 2000 May;117(5 Suppl 1):242S-4S. doi: 10.1378/chest.117.5_suppl_1.242s.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Disease Models, Animal
  • Disease Progression
  • Instillation, Drug
  • Keratolytic Agents / therapeutic use*
  • Male
  • Pancreatic Elastase / administration & dosage
  • Pancreatic Elastase / toxicity*
  • Pulmonary Alveoli / drug effects*
  • Pulmonary Alveoli / physiopathology
  • Pulmonary Emphysema / chemically induced
  • Pulmonary Emphysema / physiopathology
  • Pulmonary Emphysema / prevention & control*
  • Rats
  • Rats, Sprague-Dawley
  • Respiratory Function Tests
  • Tomography, X-Ray Computed
  • Trachea
  • Treatment Outcome
  • Tretinoin / therapeutic use*

Substances

  • Keratolytic Agents
  • Tretinoin
  • Pancreatic Elastase