Chest
Clinical InvestigationsSleep and BreathingPrevalence of Sleep-Disordered Breathing and Continuous Positive Airway Pressure Compliance: Results in Chinese Patients With First-Ever Ischemic Stroke
Section snippets
Materials and Methods
We screened 80 consecutive patients for inclusion in this study who had been admitted with acute stroke to the Prince of Wales Hospital, an acute-care teaching hospital, over a period of 3 months. A control group of 25 volunteers, who were matched for age and body mass index (BMI), were recruited from the same hospital.
Results
Of the 80 consecutive patients with acute stroke who we screened for this study, 16 patients (20%) were excluded because of radiographic evidence of hemorrhagic stroke. Of the remaining 64 patients, 51 patients met the inclusion criteria and consented to the study. There were 23 women and 28 men with a mean age of 64.2 ± 13.0 years, a mean BMI of 24.3 ± 4.4 kg/m2, a mean neck circumference of 38.1 ± 3.4 cm, a mean systolic BP of 168 ± 25 mm Hg, and a mean diastolic BP of 89 ± 15 mm Hg.
Discussion
This study has shown a high prevalence of significant obstructive SDB, arbitrarily defined as an AHI of ≥ 20 events per hour of sleep, among our patients following a first-ever ischemic stroke in the acute phase compared to the control group (49% vs 24%, respectively; p = 0.04). The prevalence of snoring prior to stroke was 53%, while 55% of our patients experienced hypertension. Daytime sleepiness was reported by 47% of patients and was graded as severe in 17.6%. There were fewer patients with
Acknowledgment
The authors thank Mr. W.C. Shum (Neurology RN) for collecting the stroke data and Sisters Mabel Tong, Fanny Chan, M.Y. Leung, and Ms. Erica Lee for their technical support with the sleep study and for providing CPAP education to our patients. We would also like to thank Drs. Timothy Kwok, K.H. Sze, and C.M. Lum for their input to our original research protocol, and Ms. Doris Chan and Dr. Anthony T. Chan for their statistical analysis for this project.
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This project was funded by Chinese University of Hong Kong direct grant No. 2084008.