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Clinical Investigations: Sleep and BreathingThe Effect of a Mandibular Advancement Device on Apneas and Sleep in Patients With Obstructive Sleep Apnea
Section snippets
Subjects
Forty-three men and four women who did not accept treatment with nasal continuous positive airway pressure or were not offered that treatment because of mild obstructive sleep apnea were invited to participate in the present study. Twenty-six patients were consecutive and thereafter only patients with an obstructive apnea-hypopnea index of >20 according to preceding sleep apnea recordings were included. Three men of the invited 47 patients refused to take part in the study and were thus
General Findings
Mild sleep apnea (obstructive apnea-hypopnea index <20) was defined in 21 of the 44 patients, moderate sleep apnea (obstructive apnea-hypopnea index 20-40) was found in 15 patients, and severe sleep apnea (obstructive apnea-hypopnea index≧40) was found in 8 patients. The three severity groups did not differ in terms of age, body mass index, total sleep time, and the percentage of sleep spent in the supine position. Medication, body mass index, and total sleep time did not differ between the two
Discussion
In the present study, the mandibular advancement device reduced the obstructive apnea-hypopnea index and the arousal index and improved the sleep stage patterns in patients with mild, moderate, and severe sleep apnea. Satisfactory results were found more frequently in those with mild apnea than in subjects with severe apnea. More than 50% of patients who had unsatisfactory results with the device still reported a satisfactory effect on snoring. These patients were regarded as suffering from
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Supported by grants from The Swedish Association for Heart and Lung Patients and The Swedish Dental Society.