Chest
Clinical Investigations: Infectious DiseasesBronchoscopic Evaluation of Pulmonary Infiltrates Following Bone Marrow Transplantation
Section snippets
Patient Demographics
We retrospectively studied the records of all BMT recipients who underwent FOB between May 1990 (initiation of the BMT program) and September 1994 at the Bowman Gray School of Medicine/Wake Forest University Medical Center and North Carolina Baptist Hospital, Winston-Salem. Patients were identified via hospital discharge coding through the medical records department. Data were obtained by review of all patient charts, bronchoscopy reports, and BMT records.
Laboratory and Chest Radiographic Data
Laboratory data from the day of FOB
Patient Demographics and Laboratory Data
During the period of review, 305 patients underwent BMT, including 224 (73%) receiving autologous and 81 (27%) allogeneic transplants. Of these, 71 patients underwent FOB, of whom 31 (43%) were women and 40 (57%) were men. The mean age of patients undergoing FOB was 38 years (range, 20 to 58 years). The indications for BMT in patients undergoing FOB are summarized in Table 1. The most common underlying condition was non-Hodgkin's lymphoma (28%). Mean±SD results of laboratory data obtained the
DISCUSSION
The spectrum of pulmonary complications and their temporal relationships to BMT have been reviewed extensively.1, 2, 3, 4, 5, 6,8,10,19, 20, 21, 22 Over a 4-year period at our center, 71 (23%) of 305 BMT recipients underwent FOB for the further evaluation of pulmonary infiltrates, a frequency similar to the experience at other centers.16, 19 Allogeneic BMT recipients develop pulmonary complications at a much higher frequency than those receiving autologous BMT. In addition, a greater proportion
ACKNOWLEDGMENT
The authors wish to thank Drs. Norman Adair, Julia Cruz, Robert Chin, and James Perry for their invaluable assistance with review and preparation of the manuscript, and to Tracey Carroll, Sherry Smith, and the Medical Records Staff of North Carolina Baptist Hospital for their assistance with data collection.
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2022, Diagnostic Microbiology of the Immunocompromised Host
Presented at the Annual Meeting of the American Thoracic Society, Seattle, May 27, 1995.