Chest
Original ResearchCoughImpact of Cough Across Different Chronic Respiratory Diseases: Comparison of Two Cough-Specific Health-Related Quality of Life Questionnaires
Section snippets
Study Population
The study was conducted over a 1-year period between August 2003 and August 2004. Consecutive unselected patients with chronic cough referred to a Specialist Cough Clinic at the Belfast City Hospital were recruited together with patients with clinically stable asthma, COPD, or bronchiectasis attending general respiratory outpatient review clinics. The latter three patient groups were recruited consecutively and not because they reported cough as a prominent or troublesome symptom. All cough
Results
Table 1 contains baseline characteristics of the 147 patients recruited to the four groups as well as test statistics for comparisons of these characteristics between the groups. Diagnostic categories in the chronic cough group were as follows: gastroesophageal reflux, 35%; asthma, 21%; idiopathic cough, 12%; postnasal drip, 7%; postviral, 6%; eosinophilic bronchitis, 6%; and other, 13% (eg, angiotensin-converting enzyme inhibitor-related cough, pulmonary fibrosis). There was a significant
Discussion
This is the first study to compare the impact of cough on HRQoL across a range of common chronic respiratory diseases using validated cough-specific quality of life questionnaires. We have demonstrated that the magnitude of cough-specific HRQoL impairment is similar among all respiratory disease groups studied and is greatest among female patients. Generic measures of HRQoL in COPD patients were significantly lower than chronic cough, asthma, and bronchiectasis patients, and this appeared to be
References (22)
- et al.
Evaluation of a cough-specific quality-of-life questionnaire
Chest
(2002) - et al.
Cough in COPD: correlation of objective monitoring with cough challenge and subjective assessments
Chest
(2006) - et al.
High resolution CT in children with cystic fibrosis: correlation with pulmonary functions and radiographic scores
Eur J Radiol
(2001) - et al.
Gender differences in health-related quality of life in patients complaining of chronic cough
Chest
(2004) - et al.
A comparison of gender differences in health-related quality of life in acute and chronic coughers
Chest
(2005) - et al.
Impact of chronic cough on quality of life
Arch Intern Med
(1998) - et al.
Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ)
Thorax
(2003) EuroQol: a new facility for the measurement of health-related quality of life; the EuroQol Group
Health Policy
(1990)- et al.
Evaluation and outcome of patients with chronic non-productive cough using a comprehensive diagnostic protocol
Thorax
(1998) - et al.
The diagnosis and management of chronic cough
Eur Respir J
(2004)
Cystic fibrosis: scoring system with thin-section CT
Radiology
Cited by (104)
Risk Factors for Persistent Chronic Cough During Consecutive Years: A Retrospective Database Analysis
2022, Journal of Allergy and Clinical Immunology: In PracticeCitation Excerpt :The present study also documented increased disease burden in patients with PCC compared with those without PCC including significantly more frequent (1) respiratory, gastrointestinal, cardiac, and psychological comorbidities and dispensed medications to treat these disorders; (2) potential cough complications, particularly stress incontinence and sleep disturbances; (3) dispensing of antitussives to treat cough; and (4) HCRU. We and others have reported an increase in the frequency of respiratory and gastrointestinal comorbidities in patients with CC.4,9,10,18,20,21 The present study further shows that the comorbidity burden is greater in those CC patients with PCC compared with those CC patients without PCC.
Patient-Reported Burden of Chronic Cough in a Managed Care Organization
2021, Journal of Allergy and Clinical Immunology: In PracticeIs the Leicester Cough Questionnaire useful for nontuberculous mycobacterial lung disease?
2021, Respiratory InvestigationChronic Cough: Characterizing and Quantifying Burden in Adults Using a Nationwide Electronic Health Records Database
2024, Journal of Healthcare Informatics Research
The authors have no conflicts of interest to disclose.
Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml).