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ORIGINAL RESEARCHASTHMASymptom Perception in Pediatric Asthma: Resistive Loading and In Vivo Assessment Compared
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Sample
The subjects in this study were 78 children aged 7 to 17 years (mean ± SD, 11.4 ± 2.1 years) recruited for participation in Rhode Island (n = 42) and Texas (n = 36). In Rhode Island, subjects came largely from physician and emergency department referrals. In Texas, they were recruited from an asthma summer camp. This study was reviewed and approved by the appropriate institutional review board at each site, and subjects and parents gave informed consent prior to participation. Demographic
Results
Means and SDs of the key predictor and outcome variables are presented in Table 2.
Discussion
Three studies in the literature have compared resistive loading techniques with laboratory-induced bronchoconstriction, with mixed results. Two studies1314 found a significant relationship between the methods of assessing perception, and one study15 did not. The present study is the first to examine the relationship between naturalistic and psychophysical approaches to quantifying symptom perception in asthmatic children. In a reasonably large sample using the best equipment available in
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This work was performed at Rhode Island Hospital, Providence, RI, and The University of Texas Medical Center, Tyler, TX.
This work was supported by National Heart, Lung, and Blood Institute grant 2R01- HL45157.
The authors have no conflicts of interest to disclose.